When you're dealing with mice, you may not be sure when it's time to call in a professional. Often it's easy to get rid of them yourself. However , there may be signs you will need pro services to handle the rodent infestation you're having. Some of the signs include droppings and smudges even once you have used all the tricks of the trade to remove them yourself. If they're still getting in after sealing holes, then it may be time to call a professional.